Ruaridh Jackson, Jon Welsh and James Eddie start for Sean Lineen's team while Rob Dewey is on the bench.
Sean said: “The players have all bought into what we are trying to achieve and they realise this is a stepping stone towards playing for Scotland in the Six Nations.
“Last year, Scotland A enjoyed a huge amount of success – including the Nations Cup triumph in Romania – and only lost one match in 2009.
“Unfortunately that result was against Ireland A, so we are keen to set the record straight and produce a positive performance in Belfast.
“All of the players involved are pushing for selection in the senior team and there is the right balance in the squad with youth and experience."
Scotland A
15 Jim Thompson (Edinburgh)
14 Nikki Walker (Ospreys)
13 Ben Cairns (Edinburgh)
12 Nick De Luca (Edinburgh)
11 Simon Danielli (Ulster)
10 Ruaridh Jackson (Glasgow Warriors)
9 Mike Blair (Edinburgh) CAPTAIN
1 Jon Welsh (Glasgow Warriors)
2 Dougie Hall (Glasgow Warriors)
3 Euan Murray (Northampton Saints)
4 Scott MacLeod (Edinburgh)
5 Jim Hamilton (Edinburgh)
6 James Eddie (Glasgow Warriors)
8 Scott Gray (Northampton Saints)
7 Roddy Grant (Edinburgh)
Replacements
16 A Kelly (Edinburgh)
17 Kyle Traynor (Edinburgh)
18 Craig Hamilton (Edinburgh)
19 Fraser McKenzie (Edinburgh)
20 Greig Laidlaw (Edinburgh)
21 Rob Dewey (Glasgow Warriors)
22 John Houston (Edinburgh)