Glasgow head coach Gregor Townsend said: "We've had two good wins this season, but we know we'll have to put in a better performance tomorrow if we're to keep the momentum going.
"The Dragons are a physical side, both in how they are set up defensively and also their desire to contest at ruck time. They also have some very good ball carriers throughout their side.
"They were unlucky not to win both of their opening games, which were very close and we are well aware that we lost to them home and away last season, so it is a tough challenge that awaits us at Rodney Parade.”
15 Stuart Hogg
14 Tommy Seymour
13 Alex Dunbar
12 Peter Horne
11 DTH van der Merwe
10 Duncan Weir
9 Nikola Matawalu
1 Gordon Reid
2 Kevin Bryce
3 Euan Murray
4 Tim Swinson
5 Leone Nakarawa
6 Robert Harley
7 Tyrone Holmes
8 Josh Strauss (Captain)
Replacements
16 Fraser Brown
17 Alex Allan
18 Rossouw de Klerk
19 James Eddie
20 Chris Fusaro
21 Adam Ashe
22 Henry Pyrgos
23 Lee Jones
Not available due to injury: Michael Cusack (medical/illness), Ryan Grant (shoulder), Jonny Gray (chest/ribs), Dougie Hall (arm), Sean Lamont (foot), Pat MacArthur (head), Sean Maitland (ankle), Finn Russell (shoulder), Richie Vernon (achilles), Jon Welsh (shoulder) and Ryan Wilson (shoulder)