Fraser Brown drops to the bench with Ross Ford starting at hooker. Matt Scott takes the bench place vacated by the injured Mark Bennett.
Scotland
15 Stuart Hogg (Glasgow Warriors)
14 Tommy Seymour (Glasgow Warriors)
13 Huw Jones (Stormers)
12 Alex Dunbar (Glasgow Warriors)
11 Tim Visser (Harlequins)
10 Finn Russell (Glasgow Warriors)
9 Ali Price (Glasgow Warriors)
1 Gordon Reid (Glasgow Warriors)
2 Ross Ford (Edinburgh Rugby)
3 Zander Fagerson (Glasgow Warriors)
4 Richie Gray (Toulouse)
5 Jonny Gray (Glasgow Warriors)
6 John Barclay CAPTAIN (Scarlets)
7 Hamish Watson (Edinburgh Rugby)
8 Ryan Wilson (Glasgow Warriors)
Substitutes
16 Fraser Brown (Glasgow Warriors)
17 Allan Dell (Edinburgh Rugby)
18 Simon Berghan (Edinburgh Rugby)
19 Tim Swinson (Glasgow Warriors)
20 Cornell Du Preez (Edinburgh Rugby)
21 Henry Pyrgos (Glasgow Warriors)
22 Duncan Weir (Edinburgh Rugby)
23 Matt Scott (Gloucester)