Adam Hastings starts for Currie against Boroughmuir at Malleny Park while Kaleem Barreto is at scrum-half for a Marr side that host Hawick at Fullarton Park.
Ayr travel to take on Melrose with Brandon Thomson, George Stokes, Stafford McDowall and Robbie Smith all starting.
Grant Stewart, Patrick Kelly, Robert Beattie and Sam Yawayawa feature Glasgow Hawks' visit to Goldenacre to take on Heriot's.
Stirling County host Watsonians with Adam Nicol and Hamilton Burr included in the Bridgehaugh pack.