Of the 23-man squad named, 11 players are products of the BT Sport Scottish Rugby Academy.
In the centre, Stafford McDowell - one of two players in the starting XV to feature in last summer's World Rugby U20 Championship - is joined by Strathallan School product Mark New.
Hooker Robbie Smith is named as captain and will pack down alongside Edinburgh Accies duo Shaun Gunn and Finlay Richardson - who complete the powerful front-row trio.
In the second-row, Jamie Hodgson is joined by Racing 92's Ewan Johnson, whilst Archie Erksine, Guy Graham and Devante Onojaife form an abrasive back-row.
15 Paddy Dewhirst (Ayr)*
1 Shaun Gunn (Edinburgh Accies)*
2 Robbie Smith (Ayr)* CAPTAIN
3 Finlay Richardson (Edinburgh Accies)
4 Ewan Johnson (Racing 92)
5 Jamie Hodgson (Watsonians)*
6 Archie Erskine (Boroughmuir)*
7 Guy Graham (Hawick)
8 Devante Onojaife (Northampton Saints)
16 Bradley Clements (Ealing)
17 Nathan McBeth (Lions)
18 Murphy Walker (Strathallan School)*
19. Harry Butler (Hartpury)
20 Rory Darge (Melrose)*
21 Charlie Chapman (Gloucester)
22 Ross Thompson (Glasgow Hawks)*
23 Rory McMichael (Glasgow Hawks)
*BT Sport Scottish Rugby Academy supported player 2017-18
**BT Sport Scottish Rugby Academy Stage 3 player 2017-18