The 29-year-old made his debut for the Warriors in 2010 meaning his new deal will take his time at the club to over a decade.
The open-side flanker has captained the side four times this season in the absence of Callum Gibbins and Ryan Wilson, winning all four including Glasgow's 14-man victory over the Scarlets in December.
Fusaro said: "Next season will be my 10th year with the club and it's been a huge honour to have called it my home for such a long time and to be able to continue to do so.
"I live close to Scotsotun, my best friends are members of the squad and I'm really enjoying my rugby under Dave and the rest of the coaches. It was an easy decision for me and my family to make."
Glasgow Warriors Head Coach Dave Rennie said: "I can't speak highly enough of Fuzzy. On and off the pitch he is an incredible professional and our environment will only benefit from his involvement for the next two years.
"He is currently playing some of his best rugby and sets a fantastic example to young players coming through the ranks here at Scotsotun."