Lee Jones will make his first appearance for the club in 22 months having not pulled on a Glasgow jersey since a 9-3 win over the Ospreys at Scotstoun in January 2019 due to injury and the COVID-19-enforced suspension of the 2019/20 season.
Jones is one of three changes to the starting lineup that took to the field against Munster on Monday night, as Wilson's men go in search of a first win in five matches.
There's a return to the Glasgow matchday 23 for Jamie Dobie following injury, as the teenage scrum-half is included after missing the club's last two fixtures.
Huw Jones is also selected amongst the replacements following his release from Scotland camp, lining up in the 23 jersey for the trip to Rodney Parade.
The replacements are completed by Samoan international TJ Ioane, who rotates to the bench after four consecutive starts in the back row.
Speaking about his selection, Wilson told glasgowwarriors.org: "This weekend we welcome back guys like Lee, Jamie, Kiran from injury, and Huw Jones returns from Scotland camp.
"For 70 minutes last week it was a two point game and we fell away at the end. Tomorrow is a real opportunity for us to improve on our recent performances.
"We know the Blues will present a tough test for us, and we know that we'll need to bring the energy and intensity I know this squad is capable of."
15 Glenn Bryce