Sebastian Cancelliere's inclusion is the only alteration to the side that claimed a dominant 22-7 victory over Exeter last time out, as Danny Wilson's men look to start their trophy defence on the front foot.
George Turner packs down once again at hooker, joining Scotland colleagues Jamie Bhatti and Zander Fagerson in the front-row.
Jack Dempsey continues at number eight after his Player of the Match-winning display against Exeter last weekend, as Rory Darge and Matt Fagerson join the Australian as part of a dynamic back-row triumvirate.
Ali Price continues as captain in the absence of club co-captains Ryan Wilson and Fraser Brown, with Ross Thompson lining up at fly-half 51 weeks on from his professional debut against the men from the capital.
On the bench, Johnny Matthews continues in the number 16 jersey, having rumbled over for his first try in European competition in last weekend's victory over Exeter.
Kiran McDonald and Tom Gordon retain their places after coming off the bench against Exeter, whilst Duncan Weir's selection sees the fly-half in line for his first 1872 Cup clash for Glasgow since the 2015/16 season.
Speaking about his selection, Head Coach Danny Wilson told glasgowwarriors.org: "Coming off the back of a good win against Exeter in Europe, we know we will have to match that intensity and physicality to give ourselves an opportunity to win a derby match.
"Edinburgh are in a good vein of form with a big win against Saracens in their last game.
"We're looking forward to the challenge of welcoming them to Scotstoun tomorrow evening."
15 Josh McKay