The Scottish international centre left Warriors at the end of the 2020/2021 season to join up with the English Premiership club.
Jones re-joins Danny Wilson's playing group on a multi-year contract having initially put pen to paper with the Warriors in the summer of 2017. The former Stormer sits one appearance shy of a half-century in Glasgow colours as he returns to Scotstoun.
His first try for the club came in December 2017, crossing the whitewash against Edinburgh in the 1872 Cup first leg at BT Murrayfield.
Jones went on to register 12 tries in total during a five-year stint at Scotstoun, including four tries in 13 appearances during the 2020/21 campaign under Danny Wilson.
A summer switch to Harlequins has seen him continue to showcase the attacking skills that have made him one of Scottish rugby's most feared attacking weapons, touching down for seven tries in his 27 appearances for the London outfit to date.
Indeed, his form since the turn of the year has been nothing short of exemplary - selected four times in the official Premiership Team of the Week, Jones has also been named as the league's Player of the Round on two separate occasions in the 2021/22 season.
Capped 32 times by Scotland thus far in his career, Jones has also brought BT Murrayfield to its feet with a host of memorable scores in the famous dark blue jersey.
Tries in all three November Tests in 2017 - against Samoa, New Zealand and Australia - were followed by an unforgettable brace against England in the 2018 Guinness Six Nations, part of a haul of 13 tries for his country.
Close friends with team-mate Oli Kebble, Jones is also a former student of the University of Cape Town.
When asked about his return, Jones told glasgowwarriors.org: "I missed Oli loads, and I think I left the oven on!"
He continued: "In all seriousness, I'm really looking forward to going back to Glasgow.
"I lived there for five years and I made a lot of friends and memories, and I'm looking forward to making more both on and off the field in the seasons ahead.
"There's a great core group of players at Glasgow that want to take the club forward and I'm really keen to be a part of that.
"I've gained a lot of valuable experience playing for Harlequins this season and I'm excited to return and show how I've developed as a player, and to pull on the Glasgow Warriors jersey again."
Head Coach Wilson welcomed Jones's return, saying: "We're really excited to bring Huw back to the club.
"Huw has shown for both Glasgow, and more recently for Harlequins, he is a real attacking presence at both 13 and 15.
"We wanted to add to our midfield to bring depth to an already strong position and the fact Huw can genuinely play other outside back positions will further enhance our squad depth for next season."