Richie Gray, Huw Jones and George Turner are all available after recovering from injuries picked up in the Six Nations.
Gray hasn't played since Scotland's Six Nations opener against Wales when he suffered injury while Jones and Turner were last in action in the final game against Ireland.
Gray suffered a bicep injury while it was a nasty finger problem for Jones while Turner picked up a foot injury before then needing to undergo surgery for appendicitis.
The trio's return would boost Glasgow ahead of the URC play-offs.
Glasgow assistant coach Peter Murchie is glad to see the players back in action and says that even if it's decided that they won't be involved this weekend, their return helps prepare the rest of the squad too.
Speaking to Scotland Rugby News, Murchie said: "It's certainly looking better. Richie Gray's been training for a couple of weeks now. He's been working away while we've been in South Africa, especially with the A group who played against the [Ayrshire] Bulls on Friday night and got a good result.
"He's been training away with them. The same with George Turner. They're certainly closer, especially Richie, to being involved. Huw Jones as well, he's in the same boat, he's been training with the A team guys and they're all looking sharp.
"They've got a chance. It's massive to have players coming back into the group, even just for training standards. If you've got 30 guys on the pitch at the same time going at each other, it means you have to be on it, so it's a big boost having them back in. They're obviously experienced guys."
Murchie also confirmed Tom Jordan has passed all the protocols and had no issues in training after failing an HIA during the defeat to the Lions in South Africa.