After being named as Scotland captain last week, Sione Tuipulotu will lead the team out for the first time this weekend.
With only home-based players available due to the match taking place outside the international window, Sione will partner Huw Jones in the centre.
After an impressive Guinness Six Nations earlier this year and scoring two tries against Chile on summer tour, Kyle Rowe is named at full-back. Whilst Rowe usually starts on the wing for Glasgow, he has proved impressive on the field with his recent footballing skills. Rowe is also currently one of the top try-scorers in the United Rugby Championship so far this season.
A URC-winning back-row will start the match with Glasgow Warriors' Matt Fagerson, Rory Darge and Jack Dempsey all named.
Zander Fagerson and Scott Cummings also start in the forward pack.
Max Williamson played in all four Skyscanner Summer Tour matches and will be looking to add to his tally, from the bench. Gregor Brown and Jamie Dobie were also heavily involved on tour and they are selected in the matchday 23 along with Glasgow Warriors centre Stafford McDowall.
Now eligible for Scotland on residency grounds, Tom Jordan will be eying his Scotland debut having been on form for Glasgow Warriors, featuring in every game of Warriors' URC-winning 2023/24 campaign, making his 50th appearance in the final.
Scotland
15 Kyle Rowe - Glasgow Warriors (7)
14 Darcy Graham - Edinburgh Rugby (39)
13 Huw Jones - Glasgow Warriors (50)
12 Sione Tuipulotu - Glasgow Warriors (27) CAPTAIN
11 Duhan van der Merwe - Edinburgh Rugby (41)
10 Adam Hastings - Glasgow Warriors (30)
9 Ali Price - Edinburgh Rugby (67)
1 Pierre Schoeman - Edinburgh Rugby (34)
2 Ewan Ashman - Edinburgh Rugby (19)
3 Zander Fagerson - Glasgow Warriors (67)
4 Grant Gilchrist - Edinburgh Rugby (72)
5 Scott Cummings - Glasgow Warriors (39)
6 Matt Fagerson - Glasgow Warriors (47)
7 Rory Darge - Glasgow Warriors (22) VICE-CAPTAIN
8 Jack Dempsey - Glasgow Warriors (20)
Substitutes
16 Dylan Richardson - The Sharks (3)
17 Rory Sutherland - Glasgow Warriors (33)
18 D'arcy Rae - Edinburgh Rugby (1)
19 Max Williamson - Glasgow Warriors (4)
20 Gregor Brown - Glasgow Warriors (3)
21 Jamie Dobie - Glasgow Warriors (6)
22 Tom Jordan - Glasgow Warriors (uncapped)
23 Stafford McDowall - Glasgow Warriors (5)