Jones joins Glasgow Warriors team-mates Scott Cummings and Sione Tuipulotu in the matchday 23 as Andy Farrells squad look to bounce back from defeat against Argentina last weekend.
Cummings is promoted to the starting XV after coming off the bench last weekend while Tuipulotu moves to inside-centre after starting in the number 13 jersey against Argentina in Dublin.
Finn Russell and Pierre Schoeman are the other Scots involved in this weekend's match.
British & Irish Lions
15 Elliot Daly
14 Mack Hansen
13 Garry Ringrose
12 Sione Tuipulotu
11 James Lowe
10 Finn Russell
9 Tomos Williams
1 Pierre Schoeman
2 Dan Sheehan (Captain)
3 Tadhg Furlong
4 Scott Cummings
5 Joe McCarthy
6 Tadhg Beirne
7 Josh van der Flier
8 Henry Pollock
Substitutes
16 Ronan Kelleher
17 Andrew Porter
18 Will Stuart
19 Ollie Chessum
20 Jack Conan
21 Alex Mitchell
22 Huw Jones
23 Marcus Smith