McDowall captains the Scots in the non-capped fixture - his sixth consecutive appearance for his country.
Elsewhere, Ollie Smith will pull on a Scotland shirt for the first time since the 2023 Rugby World Cup after being named at full-back, the Marr RFC product having caught the eye in the latter half of the 2024/25 campaign following his return from a long-term knee injury.
Fin Richardson starts at tight-head for the first time, as he continues to push for a senior Scotland debut after an impressive debut campaign in Glasgow colours.
An all-Glasgow half-back combination sees George Horne and Adam Hastings link up at nine and 10 respectively, the former also serving as one of McDowall's vice-captains for the fixture.
Nathan McBeth joins Richardson in the front row to make his first Scotland appearance since last summer's tour of the Americas, the loose-head having scored in four successive fixtures for the Warriors earlier in 2025.
Max Williamson and Gregor Brown provide cover in the loose forwards amongst the replacements, the pair - like McBeth - having made their senior Scotland debuts on the 2024 summer tour.
Jamie Dobie rounds out the Glasgow cohort, providing cover at scrum-half and on the wing in a six-two split of forwards and backs on the bench.
The Maori include former Glasgow back Cole Forbes.
Scotland
15 Ollie Smith - Glasgow Warriors (9)
14 Harry Paterson - Edinburgh Rugby (3)
13 Rory Hutchinson - Northampton Saints (8)
12 Stafford McDowall - Glasgow Warriors - CAPTAIN (13)
11 Arron Reed - Sale Sharks (3)
10 Adam Hastings - Glasgow Warriors (32)
9 George Horne - Glasgow Warriors - VICE CAPTAIN (36)
1 Nathan McBeth - Glasgow Warriors (2)
2 Patrick Harrison - Edinburgh Rugby (3)
3 Fin Richardson - Glasgow Warriors (uncapped)
4 Marshall Sykes - Edinburgh Rugby (2)
5 Cameron Henderson - Leicester Tigers (1)
6 Josh Bayliss - Bath Rugby - VICE-CAPTAIN (10)
7 Andy Onyeama-Christie - Saracens (8)
8 Ben Muncaster - Edinburgh Rugby (2)
Substitutes
16 George Turner - Harlequins (45)
17 Alec Hepburn - Scarlets (4)
18 Will Hurd - Leicester Tigers (8)
19.l Max Williamson - Glasgow Warriors (6)
20 Gregor Brown - Glasgow Warriors (9)
21 Alexander Masibaka - Montpellier (uncapped)
22 Fergus Burke - Saracens (uncapped)
23 Jamie Dobie - Glasgow Warriors (12)