The Warriors, URC champions in 2024, currently sit top of the table but risk being overtaken when they face the Stormers in Cape Town tomorrow. A defeat in South Africa would erase Glasgow's four-point lead not only over the Stormers but also Leinster Rugby.
If Glasgow finish in the top two, they would secure home advantage throughout the play-offs. A home quarter-final would be held at Scotstoun on the weekend of May 29-31. However, a home semi-final would have to move to Murrayfield Stadium on the weekend of June 6, as Scotstoun will be unavailable.
Should Franco Smith's side reach the final on June 20 as the highest-ranked team, they would be entitled to host it in Scotland - but finding a venue has proven difficult. Hampden Park is unavailable due to Take That concerts. Celtic Park will have its pitch relaid after the football season, while Ibrox Stadium presents issues with pitch dimensions. Murrayfield is also expected to be unavailable because it falls between major concerts by Zach Bryan and Luke Combs.
The situation raises questions about Scottish Rugby's decision to schedule concerts before the rugby season concludes, especially given Glasgow's recent success and the known unavailability of Scotstoun for a potential final.
The Warriors have also explored other venues. St James' Park is unavailable due to pitch work, while the Stadium of Light is booked for a concert.
Head coach Franco Smith said the situation has become a source of motivation:
"When we heard of it the first time, one was a little bit disappointed, obviously, but we've known this now for quite a while. And we learned to deal with it.
"Now it's not a hindrance, it's more of a motivation for us to become the best of our best. To be able to win, not at Scotstoun.
"So, yes, obviously, the original announcement was a disappointment to everybody. But that's human but we've since then moved on.
"Now that we have been leading the log, all these conversations obviously happen. We try to turn it into a motivator.'
As a result, Glasgow - who remain top with four games left - are considering taking a 'home' final to Affidea Stadium in Belfast, home of Ulster Rugby. The venue was the site of their first league title in 2015 when they defeated Munster Rugby in the PRO12 final.