Under normal circumstances, finishing top at the end of the regular season guarantees home advantage throughout the play-offs, including hosting the final should Franco Smith's side progress that far.
That, however, would not be the reward for Glasgow if they manage to secure their first bonus-point victory in Belfast since 2008.
The Warriors are set to host their quarter-final at Scotstoun in a fortnight. But should they advance, a potential semi-final would instead be staged at Murrayfield.
Smith's side must vacate Scotstoun as the venue prepares to host Commonwealth Games events, meaning the club would still play the last four in familiar surroundings - albeit away from their home ground.
A far bigger issue, however, looms over the location of a potential URC final should Glasgow make it that far.
Murrayfield is unavailable due to a concert by country music star Zach Bryan, while Celtic Park - which hosted the PRO14 final in 2019 - cannot be used because of planned pitch replacement work. Ibrox also fails to meet URC regulations.
Hampden Park, where Glasgow staged their last two home 1872 Cup derbies against Edinburgh, is likewise unavailable because of scheduled concerts.
URC rules require any final venue to have a minimum capacity of 12,000, ruling out Firhill and leaving Glasgow without a viable alternative venue in the city.
Options elsewhere in Scotland have also been exhausted. Hibernian's Easter Road and Hearts' Tynecastle are unavailable, ending hopes of taking the final to Edinburgh. Kilmarnock are replacing the artificial surface at Rugby Park - previously used twice by Scotland - while Aberdeen's Pittodrie was also deemed unsuitable.
Enquiries were made about venues in Northern England, including Sunderland's Stadium of Light and Newcastle United's St James' Park, but both were unavailable because of concerts.
Scotland Rugby News understands Glasgow have informed URC officials that their preferred option for a potential home final would be Ulster's Affidea Stadium - the same venue where they play this weekend.
The 18,000-capacity ground is available, but it is understood the URC are leaning towards switching home advantage should Glasgow reach the final.
That decision would reportedly be based on maximising exposure and revenue for the competition's showpiece occasion by staging it at a significantly larger venue, most likely in South Africa or Dublin.
A URC spokesperson confirmed that a decision is expected next week once the regular season concludes and the eight play-off teams are confirmed.
Questions over the sporting integrity of the competition are likely to arise should Glasgow reach the final only for the URC to reject their preferred venue in Belfast.
Asked specifically about the possibility of the final being moved, Warriors head coach Franco Smith responded diplomatically.
"For now, we will have to deal with that when we get to that final.
"It makes it difficult, but it doesn't influence the motivation for the current challenge, which is the one tomorrow.
"I feel if we can't control that, we must deal with what we can. That's been the mentality here.
"If there's injury or decisions gone against us or travel didn't work out well, whatever influences, I think that we can't control. We must learn to manage that and deal with it like all sportsmen at the top end must be able to do."
On the prospect of not playing the final in Scotland, Smith added: "Obviously, that's a frustration, but it's something we can do nothing about at the moment.
"We'll have to play the card that's played for us. Two, we're not in the final yet and I don't want to be sidetracked at the moment about things that we can't control.
"Our mission is to get through this game this weekend, playing the brand that we know we can play away from Scotland and allowing ourselves to progress to give us the best opportunity.
"Part of it is the venue, but for now to be frustrated, when it was originally announced that it won't be here, that was when we were frustrated. Now we've learned to deal with it."
While Smith was reluctant to fully air his feelings on the looming URC decision before Glasgow have even secured top spot against Ulster, he admitted it would be 'fantastic' if the Warriors were allowed to stage the final in Belfast.
Glasgow won their first-ever league title in Belfast in 2015, when Alastair Kellock captained the side to PRO12 glory.
"You can play a final at the end of the day in any place," Smith said. "It's an on-the-day thing. If we get to play the final there, it will be fantastic. If we're in the final, that's going to be the next challenge for us.
"For now, to have a game this late in the competition there, obviously, if it does work out that way, it will allow us to use it as a point of reference.
"For now, that has not come to mind. It's all about the 80 minutes that we've got in front of us."