The 27-year-old made 74 appearances across an eight-year spell at the club, having made his debut against the Ospreys in 2012, after initially joining as an Elite Development Player.
Born in Livingston, Ashe earned his first Scotland cap against South Africa in Port Elizabeth on the 2014 summer tour.
Ashe crossed for 13 tries during his time in Glasgow colours, most recently crossing for a brace in a 42-22 victory over Lyon in December 2018.
In his final season with the Warriors, the former Stirling County man, turned out three times for the club, making his final appearance off the bench in December's 20-16 win over Edinburgh at Scotstoun.
"I've had an absolutely brilliant eight years with the club," Ashe told glasgowwarriors.org.
"I've been very fortunate to be involved with this club since leaving high school, and I've enjoyed every moment. I've played under a number of different coaches, made many good friendships and I can't speak highly enough of the club and staff.
"The fans have been amazing. I've got to know them on a personal level over the years, and I'll be sad not to see them week in week out. They're so loyal and turn up no matter the weather, so I want to say thank you to them.
"I feel like I've still got some of my best years ahead of me, however - I'm excited for what's to come, and I'm looking forward to the next chapter."
Ashe who is recovering from shoulder surgery will remain under the care of club's medical team for the coming months.
Also departing the club following the conclusion of the 2019/20 season is loose-head prop Charlie Capps, who will be pursuing other opportunities ahead of the new campaign.
The Harrogate-born 23-year-old made his Glasgow Warriors debut off the bench against Edinburgh last Friday, having initially joined on a one year deal in the summer of 2019 from Stade Nicois.
"Glasgow Warriors are a great club and I've really enjoyed my time here," Capps told glasgowwarriors.org.
"It's a special group of players to be part of and I wish the guys all the best for next season."
"Adam has been a long time servant of the club and his work both on and off the pitch over the last eight seasons has been that of a true professional.
"Charlie has also made and impact while here and it was great to see him make his debut on the weekend and help us get the win. Both him and Adam are good players and outstanding men with plenty of rugby ahead of them, and we wish them all the best for the next chapters in their careers."