Cheika includes Australian debutant Adam Byrnes while Felipe Contepomi, Girvan Dempsey, Bernard Jackman and Keith Gleeson are also included.
Leinster's new Aussie coach includes scrum-halves Brian O'Meara, Guy Easterby, and Brian O'Riordan.
Reggie Corrigan is still an absentee with a hand injury.
Leinster squad: (Forwards) Emmett Byrne, Will Green, John Lyne, Ronan McCormack, David Blaney, Bernard Jackman, Adam Byrnes, Ben Gissing, Des Dillon, Simon Crawford, Ciaran Potts, Niall Ronan, Keith Gleeson, Eric Miller, Jamie Heaslip.
(Backs): Guy Easterby, Brian O'Meara, Brian O'Riordan, Christian Warner, Felipe Contepomi, Kieran Lewis, Gary Brown, Brendan Burke, James Norton, Robert Kearney, Eoghan Hickey, Girvan Dempsey.