Joining the starting line-up are centre Scott Barrow and stand-off Colin Gregor.
Scrum-half Graeme Beveridge takes over the captaincy as the majority of the club's Scotland players are rested ahead of the Autumn Tests.
15 Graydon Staniforth
14 Hefin O'Hare
13 Graeme Morrison
12 Scott Barrow
11 Colin Shaw
10 Colin Gregor*
9 Graeme Beveridge CAPTAIN
1 Kevin Tkachuk
2 Scott Lawson*
3 Lee Harrison
4 Tim Barker
5 Dan Turner
6 Paul Dearlove
8 John Beattie*
7 John Barclay*
Substitutes:
16 Fergus Thomson*
17 Stuart Corsar
18 Gregor Hayter
19 Steve Swindall
20 Sam Pinder
21 Andrew Henderson
22 Eddie McLaughlin
* = Member of Scottish Institute of Sport
Not considered due to injury:
Andy Craig (ankle), Calvin Howarth (ankle), Iain Kennedy (viral bug), Donnie Macfadyen (knee), Euan Murray (recurrence of post-concussion symptoms), Jon Petrie (shoulder), Ben Prescott (shoulder), Mike Roberts (shoulder), Andrew Wilson (ankle).