Eight Glasgow Warriors are in the Scotland XV with Jack Dempsey making his first Six Nations start.
Townsend has retained his other Glasgow starters from the loss to France a fortnight ago - hooker George Turner, tighthead prop Zander Fagerson, lock Richie Gray, back row Matt Fagerson, centres Sione Tuipulotu and Huw Jones and winger Kyle Steyn.
With Dempsey selected at number 8, having previously featured from the bench against England, Wales, and France, Matt Fagerson moves to the openside flank. This is Dempsey's second Scotland start, his first coming against Argentina in the 2022 Autumn Nations Series.
A further five Glasgow Warriors replacements can feature from the bench. Scotland have opted for a full Warriors replacement front row with Fraser Brown, Jamie Bhatti, and Simon Berghan selected. Berghan wears the number 18 jersey in place of WP Nel this time. Scott Cummings is also named on the bench for a chance to earn his first Scotland cap from this campaign.
The Glasgow contingent is completed with Ali Price wearing 21, as replacement scrum half. If Price does come on, on Sunday, he will earn his 60th Scotland cap.
In addition, former Glasgow Warrior, Stuart Hogg, is in line to make his 100th Scotland appearance, starting at full back.
15 Stuart Hogg (Exeter Chiefs) - Vice-Captain - 99 caps
14 Kyle Steyn (Glasgow Warriors) 8 caps
13 Huw Jones (Glasgow Warriors) 34 caps
12 Sione Tuipulotu (Glasgow Warriors) 14 caps
11 Duhan van der Merwe (Edinburgh Rugby) 26 caps
10 Finn Russell (Racing 92) 68 caps
9 Ben White (London Irish) 12 caps
1 Pierre Schoeman (Edinburgh Rugby) 19 caps
2 George Turner (Glasgow Warriors) 33 caps
3 Zander Fagerson (Glasgow Warriors) 56 caps
4 Richie Gray (Glasgow Warriors) 72 caps
5 Jonny Gray (Exeter Chiefs) - Vice-Captain - 75 caps
6 Matt Fagerson (Glasgow Warriors) 31 caps
7 Jamie Ritchie (Edinburgh Rugby) - Captain - 39 caps
8 Jack Dempsey (Glasgow Warriors) 7 caps
16 Fraser Brown (Glasgow Warriors) 60 caps
17 Jamie Bhatti (Glasgow Warriors) 28 caps
18 Simon Berghan (Glasgow Warriors) 32 caps
19 Scott Cummings (Glasgow Warriors) 23 caps
20 Hamish Watson (Edinburgh Rugby) 55 caps
21 Ali Price (Glasgow Warriors) 59 caps
22 Blair Kinghorn (Edinburgh Rugby) 41 caps
23 Chris Harris (Gloucester Rugby) 41 caps