Ronan McCormack and Nigel Brady join Simon Best in the front row in place of Rod Moore and Paul Shields who are both named on the bench, with Best switching to tighthead prop.
With Roger Wilson, who picked up a knock against The Dragons last Friday, Andy Ward and Neil McMillan all ruled out through injury, McCall has opted for newcomer Gary Brown at No.8 with Matt Mustchin providing back-row cover from the bench.
15 Bryn Cunningham
14 Tommy Bowe
13 Kevin Maggs
12 Paul Steinmetz
11 Tyrone Howe
10 David Humphreys (Captain)
9 Kieran Campbell
1 Ronan McCormack
2 Nigel Brady
3 Simon Best
4 Gary Longwell
5 Matt McCullough
6 Campbell Feather
7 Neil Best
8 Gary Brown
Replacements:
16 Paul Shields
17 Rod Moore
18 Rowan Frost
19 Matt Mustchin
20 Neil Doak
21 Paddy Wallace
22 Jonathon Bell