Scott is at inside centre after recovering from shoulder damage sustained in training in October, an injury that subsequently required surgery.
Hugh Campbell, Glasgow's head coach, welcomed Barrow’s return. "He's a quality player," the coach commented. "It's a great opportunity to get him involved in a game like this against Ospreys, who are at the top of the league."
Scott's return is timely as another of Glasgow's centres, Andy Craig, is among five players not available tomorrow because of Scotland's opening Six Nations Championship match against France in Paris a week tomorrow. The four others resting before Paris duty are Sean Lamont, Dan Parks, Gordon Bulloch and Jon Petrie.
Graeme Morrison returns as outside centre, and Kenny Logan switches from full back to wing in place of David Millard. Glasgow Hawks' Colin Shaw returns at full back.
Calvin Howarth, who missed the Newport match because of a back strain, takes over from Dan Parks at stand-off, and Scott Lawson replaces GB as hooker. Scott's recall is the only change in the pack, with Colin Shaw's fellow Hawk, Steve Swindall, remaining at blind side. Scott and Colin played against Dragons as replacements last week.
Andy Hall, is on the verge of reaching the previously unattained milestone of 50 Celtic League games. His replacement appearance against Dragons was his forty-ninth league match. But he looks like being only second to the half-century as another Andrew, Millward, who also had had 49 league appearances, will be starting for Ospreys in the Hughenden match.
Because of international calls and injuries Glasgow have had to draw on four club players. As well as Shaw and Swindall in the starting XV, Ben Prescott, the Aberdeen prop, is on the bench, as is A J McFarlane, GHA's Scotland under-21 scrum half.
Glasgow
15 Colin Shaw
14 Rory Lamont
13 Graeme Morrison
12 Scott Barrow
11 Kenny Logan
10 Calvin Howarth
9 Graeme Beveridge
1 Kevin Tkachuk
2 Scott Lawson
3 Andrew Kelly
4 Joe Beardshaw
5 Dan Turner
6 Steve Swindall
8 Paul Dearlove
7 Cammy Mather
Replacements
16 Fergus Thomson
17 Ben Prescott
18 Andy Hall
19 John Beattie
20 A J McFarlane
21 Andy Henderson
22 David Millard