Sam missed last week's 55-7 warm-up win against Rotherham Titans after he had suffered a dead leg but he reappears to join Graeme Beveridge in competing for the No 9 shirt.
John Barclay is included as international openside flanker Donnie Macfadyen continues his rehab from knee surgery.
Glasgow Warriors' head coach Hugh Campbell said: "Donnie is very much on the mend and could well be available for selection for next Friday’s Celtic League opener against the Dragons at Hughenden.
"As far as tomorrow's match goes, Newcastle are a top Guinness Premiership side and have just returned from a tour of Japan. This will be an excellent test for us prior to the start of the Celtic League."
Glasgow Warriors' squad to play Newcastle Falcons at Kingston Park, Newcastle tomorrow (Saturday 27 August), kick-off 5.30pm
Backs – Graydon Staniforth, Colin Shaw, Rory Lamont, Eddie McLaughlin, Andy Craig, Scott Barrow, Andrew Henderson, Mike Roberts, Calvin Howarth, Dan Parks, Graeme Beveridge, Sam Pinder
Forwards – Stuart Corsar, Kevin Tkachuk, Scott Lawson, Lee Harrison, Tim Barker, Gregor Hayter, Dan Turner, Craig Hamilton, Paul Dearlove, Jon Petrie captain, John Barclay, Andrew Wilson