Ashley Smith (shoulder), Lee Harrison (foot) and Nic Fitisemanu (hamstring) will be monitored in the week.
Ian Gough will be retained by the Wales squad and Kevin Morgan is injured.
But Colin Charvis, Aled Brew, Ceri Sweeney and Gareth Cooper have been released for regional duty.
Kieran Crawford, Steve Jones, Rhys Thomas and Craig Warlow remain sidelined by injury.