Chris Laidlaw’s team will face their Welsh opponents in front of the Warrior Nation on Saturday 17 February, kicking off at 4.30pm.
The match will precede the club's BKT URC clash with the Dragons on the same day, with Franco Smith's men's squad kicking off at 7.35pm.
Both teams will participate in Glasgow Warriors' Club of Origin celebrations planned for the fixtures, with further details to announced closer to the match.
Match tickets for the individual games will NOT be sold separately and supporters will have the same seat for both fixtures.
Please note, gates will open at 4.00pm and there will be no re-admission. Once you exit the grounds you will not be permitted to re-enter.
There are currently fewer than 500 match tickets available across Scotstoun Stadium for this double-header, with a sell-out expected at the home of the Warriors.