Ruaraidh Hart co-captain's the U20s squad for the second time alongside Geordie Gwynn from Ealing Trailfinders and Brunel University.
Hart made his senior club debut for Glasgow Warriors back in February in a 40-7 win over the Dragons.
The other four players in the starting line-up include Callum Smyth, Callum Norrie, Jonny Morris, and Johnny Ventisei.
Kerr Johnston is travelling with the U20s squad this weekend.
Kick-off is at 7.00pm on Friday 15 March.
Scotland U20
15 Jack Brown* (Edinburgh Rugby)
14 Finlay Doyle (Loughborough University)
13 Johnny Ventisei* (Glasgow Warriors)
12 Findlay Thomson (Watsonians)
11 Geordie Gwynn (Ealing Trailfinders/Brunel University) - Co-Captain
10 Isaac Coates* (Edinburgh Rugby)
9 Hector Patterson* (Edinburgh Rugby)
1 Callum Smyth* (Glasgow Warriors)
2 Jerry Blyth-Lafferty* (Edinburgh Rugby)
3 Callum Norrie* (Glasgow Warriors)
4 Euan McVie* (Edinburgh Rugby)
5 Ruaraidh Hart* (Glasgow Warriors) - Co-Captain
6 Jonny Morris* (Glasgow Warriors)
7 Freddy Douglas* (Edinburgh Rugby)
8 Tom Currie* (Edinburgh Rugby)
Substitutes
16 Marcus Brogan (Hawick RFC)
17 Robbie Deans* (Edinburgh Rugby)
18 Ryan Whitefield (Biggar RFC)
19 Archie Clarke (Durham University)
20 Monroe Job (Southern Knights)
21 Eric Davey (Stirling Wolves)
22 Andrew McLean (Boroughmuir Bears)
23 Finn Douglas* (Edinburgh Rugby)
*FOSROC Scottish Rugby Contracted Academy Player