Glasgow lost their Champions Cup quarter-final away to Harlequins last time out, but return to URC action on Friday when South African side Sharks call in at Scotstoun.
Warriors currently sit second in the league table, with the top four sides guaranteed a home quarter-final, and the top two a home semi-final, should they progress.
Speaking to the BBC Scotland website, Murchie said: "We were away from home [in Europe] for a reason. There's always things to learn from every situation. We could and should have had a home tie if we'd done things differently but we didn't. Coulda, woulda, shoulda, almost. If we want to keep it in our control then we'll need to take care of our own business."
The Sharks have put their early season form behind them to record four wins in a row - including two victories over Edinburgh - and Murchie accepts his side now need to sharpen up to maintain control of their own destiny.
"We want everything to be firing. We want to take our opportunities in attack. They're big men, big units who are very physical and they've got a lot of x-factor within that.
"Defensively, you've got to be on it for 80 minutes because if you clock off, they've got individuals who can hurt you from anywhere. We need to stay on it and make sure we nullify them and get the ball back."