Tuipulotu has played every minute of his four appearances on the tour to date, opening his try-scoring account against the AUNZ Invitational XV last time out.
Jones's tally of three tries on tour to date equals the highest total in a single tour by a Glasgow Warrior in the professional era, the 31-year-old having also made 208 metres with ball in hand during his four outings in the red jersey to date.
'Huwipulotu' will line up alongside their Scottish international colleague - and former Warrior - Finn Russell.
British & Irish Lions
15 Hugo Keenan (Leinster Rugby/Ireland)
14 Tommy Freeman (Northampton Saints/England)
13 Huw Jones (Glasgow Warriors/Scotland)
12 Sione Tuipulotu (Glasgow Warriors/Scotland)
11 James Lowe (Leinster Rugby/Ireland)
10 Finn Russell (Bath Rugby/Scotland)
9 Jamison Gibson-Park (Leinster Rugby/Ireland)
1 Ellis Genge (Bristol Bears/England)
2 Dan Sheehan (Leinster Rugby/Ireland)
3 Tadhg Furlong (Leinster Rugby/Ireland)
4 Maro Itoje (Saracens/England) (Captain)
5 Joe McCarthy (Leinster Rugby/Ireland)
6 Tadhg Beirne (Munster Rugby/Ireland)
7 Tom Curry (Sale Sharks/England)
8 Jack Conan (Leinster Rugby/Ireland)
Substitutes
16 Ronan Kelleher (Leinster Rugby/Ireland)
17 Andrew Porter (Leinster Rugby/Ireland)
18 Will Stuart (Bath Rugby/England)
19 Ollie Chessum (Leicester Tigers/England)
20 Ben Earl (Saracens/England)
21 Alex Mitchell (Northampton Saints/England)
22 Marcus Smith (Harlequins/ England)
23 Bundee Aki (Connacht Rugby/Ireland)